[BEP-chemotherapy in patients with testicular tumors--is it worthwhile?]

Schweiz Med Wochenschr. 1990 Dec 8;120(49):1883-6.
[Article in German]

Abstract

Since 1985 44 consecutive patients with testicular cancer have been treated with a modified BEP regimen. 70% had metastatic disease and 30% received adjuvant therapy. After mean follow-up of 26 (8-56) months, 91% of patients are alive and all are in remission. Chemotherapy-related side effects were alopecia (100%), myelosuppression (100%), nausea/vomiting (89%) and fever (66%). Patients reported nausea has been rare. It is concluded that BEP chemotherapy is a highly effective treatment which secures complete remission or cure even in patients with advanced metastatic disease. In retrospect the patients considered the treatment worthwhile despite the stress involved.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Bleomycin / administration & dosage
  • Bleomycin / adverse effects
  • Bone Marrow Diseases / chemically induced
  • Cisplatin / administration & dosage
  • Cisplatin / adverse effects
  • Etoposide / administration & dosage
  • Etoposide / adverse effects
  • Fever / chemically induced
  • Humans
  • Lung Diseases / chemically induced
  • Male
  • Middle Aged
  • Nervous System Diseases / chemically induced
  • Retrospective Studies
  • Testicular Neoplasms / drug therapy*

Substances

  • Bleomycin
  • Etoposide
  • Cisplatin

Supplementary concepts

  • BEP protocol