Diagnosis and treatment of dural carotid-cavernous fistulas: a consecutive series of 27 patients

J Neurol Neurosurg Psychiatry. 2007 Feb;78(2):174-9. doi: 10.1136/jnnp.2006.100776. Epub 2006 Oct 6.

Abstract

Objectives: To report clinical characteristics, angiographical findings and results of endovascular treatment of patients presenting with dural carotid-cavernous fistulas (DCCFs).

Method: Retrospective analysis of 27 consecutive patients with DCCF referred to a specialised interventional neuroradiology department.

Results: Orbital and neuro-ophthalmological symptoms were the most common clinical presentation at diagnosis (n = 25). The venous drainage of the fistula involved the ipsilateral superior ophthalmic vein in 24 patients, the contralateral cavernous sinus in 6 and a leptomeningeal vein in 5 patients. Thrombosis of at least one petrosal sinus was found in 23 patients. 7 patients did not receive endovascular treatment: 3 had spontaneous DCCF obliteration, and 4 had only minor clinical symptoms and no leptomeningeal venous drainage on an angiogram. 20 patients received endovascular treatment via either a transvenous (n = 16) or a transarterial approach (n = 4). Complete occlusion of the fistula was obtained in 14 of 16 (87%) patients treated by the transvenous approach and in 1 of 4 (25%) patients treated by the transarterial approach. 16 patients had early clinical improvement after endovascular treatment. One patient had a cerebral haemorrhage after transvenous embolisation of a DCCF with leptomeningeal drainage. On follow-up, all patients treated by the transarterial route remained symptomatic, whereas 10 of 14 (71%) patients cured by the transvenous route were asymptomatic.

Conclusions: Transvenous embolisation is a safe and efficient endovascular approach to treat patients with DCCF. However, this technique requires a long learning curve.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Carotid-Cavernous Sinus Fistula / diagnosis*
  • Carotid-Cavernous Sinus Fistula / pathology
  • Carotid-Cavernous Sinus Fistula / therapy*
  • Diagnosis, Differential
  • Embolization, Therapeutic*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Retrospective Studies
  • Thrombosis / etiology
  • Treatment Outcome