Saccular aneurysms on straight and curved vessels are subject to different hemodynamics: implications of intravascular stenting

AJNR Am J Neuroradiol. 2006 Oct;27(9):1861-5.

Abstract

Our aim was to examine hemodynamic implications of intravascular stenting in the canine venous pouch (sidewall or straight-vessel) and rabbit elastase (curved-vessel) aneurysm models. Flow dynamics in stented (Wallstent) and nonstented versions were studied by using computational fluid dynamics simulations and in vitro flow visualization, with a focus on stent placement effects on aneurysmal flow stagnancy and flow impingement. Results show that sidewall and curved aneurysm models have fundamentally different hemodynamics (shear-driven versus inertia-driven) and thus stent placement outcomes.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Blood Circulation / physiology*
  • Blood Flow Velocity / physiology
  • Computer Simulation
  • Disease Models, Animal*
  • Dogs
  • Dye Dilution Technique
  • Equipment Design
  • In Vitro Techniques
  • Intracranial Aneurysm / physiopathology*
  • Intracranial Aneurysm / therapy*
  • Models, Cardiovascular
  • Rabbits
  • Recurrence
  • Stents*