Abstract
We compared hepatitis B virus (HBV) surface antigen, anti-hepatitis C virus (HCV) antibody, and HCV RNA quantification in frozen and freeze-dried serum samples to assess the usefulness of freeze-dried sera for detection of HBV and HCV. The results indicated that freeze-dried sera as well as frozen sera can be useful for serological and molecular biological analyses of HBV and HCV.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Freeze Drying
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Hepacivirus / genetics
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Hepacivirus / immunology
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Hepacivirus / isolation & purification*
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Hepatitis B / diagnosis
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Hepatitis B / virology
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Hepatitis B Surface Antigens / analysis
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Hepatitis B virus / genetics
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Hepatitis B virus / immunology
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Hepatitis B virus / isolation & purification*
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Hepatitis C / diagnosis
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Hepatitis C / virology
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Hepatitis C Antibodies / analysis
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Humans
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RNA, Viral / analysis
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Reproducibility of Results
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Sensitivity and Specificity
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Serum / virology*
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Specimen Handling / methods*
Substances
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Hepatitis B Surface Antigens
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Hepatitis C Antibodies
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RNA, Viral