Peripheral blood leukocytes as a surrogate marker for cisplatin drug resistance: studies of adduct levels and the repair gene ERCC1

Basic Life Sci. 1990:53:251-61. doi: 10.1007/978-1-4613-0637-5_20.
No abstract available

MeSH terms

  • Animals
  • Carboplatin / therapeutic use*
  • Cell Line
  • Cisplatin / pharmacology
  • Cisplatin / therapeutic use*
  • DNA / drug effects
  • DNA / genetics
  • DNA / isolation & purification
  • DNA Damage*
  • DNA Repair*
  • Drug Resistance / genetics
  • Female
  • Humans
  • Leukocytes / drug effects
  • Leukocytes / metabolism*
  • Ovarian Neoplasms / drug therapy*
  • Prognosis
  • RNA / genetics
  • RNA / isolation & purification

Substances

  • RNA
  • DNA
  • Carboplatin
  • Cisplatin