Malignant fibrous histiocytoma of the conjunctiva

Br J Ophthalmol. 1990 Oct;74(10):624-8. doi: 10.1136/bjo.74.10.624.

Abstract

Malignant fibrous histiocytoma (MFH) of the conjunctiva is an extremely rare tumour, and only three previous cases have been reported. We describe two patients with MFH of the conjunctiva: a 58-year-old white male with epibulbar tumour who had exenteration and is alive after five years' follow-up, and a 3 1/2-year-old African girl with xeroderma pigmentosum and an MFH of her right eye conjunctiva, the first reported case of this association. The characteristics and the methods of diagnosis of MFH are discussed.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Conjunctival Neoplasms / complications
  • Conjunctival Neoplasms / diagnosis
  • Conjunctival Neoplasms / pathology*
  • Eye Enucleation
  • Female
  • Follow-Up Studies
  • Histiocytoma, Benign Fibrous / complications
  • Histiocytoma, Benign Fibrous / diagnosis
  • Histiocytoma, Benign Fibrous / pathology*
  • Humans
  • Immunoenzyme Techniques
  • Keratins / metabolism
  • Lysosomes / metabolism
  • Male
  • Middle Aged
  • S100 Proteins / metabolism
  • Vimentin / metabolism
  • Xeroderma Pigmentosum / complications

Substances

  • S100 Proteins
  • Vimentin
  • Keratins