TFII-IDelta and TFII-Ibeta: unequal brothers fostering cellular proliferation

Lisa Santolin; Michael Meisterernst

doi:10.1016/j.molcel.2006.10.003

TFII-IDelta and TFII-Ibeta: unequal brothers fostering cellular proliferation

Mol Cell. 2006 Oct 20;24(2):169-71. doi: 10.1016/j.molcel.2006.10.003.

Authors

Lisa Santolin¹, Michael Meisterernst

Affiliation

¹ Gene Expression, GSF-National Research Center for Environment and Health, Institute for Molecular Immunology, Marchionistrasse 25, D-81377 München, Germany.

PMID: 17052451
DOI: 10.1016/j.molcel.2006.10.003

Abstract

Activation of the immediate-early gene c-fos through MAP kinases is a hallmark of growth factor signaling. In this issue of Molecular Cell, Roy and colleagues (Hakre et al., 2006) show that TFII-I isoforms play differential roles in this process.

Publication types

Comment
Review

MeSH terms

Alternative Splicing
Animals
Cell Nucleus / metabolism
Cell Proliferation
Cytoplasm / metabolism
Gene Expression Regulation*
Humans
Models, Biological
Phosphorylation
Protein Isoforms
Signal Transduction
Transcription Factors, TFII / chemistry
Transcription Factors, TFII / metabolism
Transcription Factors, TFII / physiology*

Substances

GTF2I protein, human
Protein Isoforms
Transcription Factors, TFII