Biosynthesis of P450 products of arachidonic acid in humans: increased formation in cardiovascular disease

Adv Prostaglandin Thromboxane Leukot Res. 1991:21A:193-6.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • 1-Methyl-3-isobutylxanthine / pharmacology
  • 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
  • 8,11,14-Eicosatrienoic Acid / analogs & derivatives*
  • 8,11,14-Eicosatrienoic Acid / metabolism
  • 8,11,14-Eicosatrienoic Acid / pharmacology
  • 8,11,14-Eicosatrienoic Acid / urine
  • Angina, Unstable / metabolism*
  • Angioplasty, Balloon, Coronary
  • Arachidonic Acid
  • Arachidonic Acids / metabolism*
  • Colforsin / pharmacology
  • Cyclic AMP / pharmacology
  • Cytochrome P-450 CYP2J2
  • Cytochrome P-450 Enzyme System / metabolism
  • Female
  • Humans
  • Oxygenases / metabolism
  • Platelet Activation / drug effects
  • Pre-Eclampsia / metabolism*
  • Pregnancy / metabolism
  • Prostaglandin Endoperoxides, Synthetic / pharmacology
  • Thrombin / pharmacology

Substances

  • Arachidonic Acids
  • Prostaglandin Endoperoxides, Synthetic
  • Colforsin
  • Arachidonic Acid
  • 11,12-epoxy-5,8,14-eicosatrienoic acid
  • 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid
  • 8,9-epoxyeicosatrienoic acid
  • 14,15-epoxy-5,8,11-eicosatrienoic acid
  • Cytochrome P-450 Enzyme System
  • Cyclic AMP
  • Oxygenases
  • Cytochrome P-450 CYP2J2
  • Thrombin
  • 8,11,14-Eicosatrienoic Acid
  • 1-Methyl-3-isobutylxanthine