Abstract
Hunter syndrome, or mucopolysaccharidosis type II, is an X-linked recessive disorder resulting from iduronate sulfatase deficiency. Typical manifestations include short stature, mental retardation, hydrocephalus, macroglossia and cardiac valvulopathy. We describe a 21-year-old patient who presented with acute ischemic stroke and evidence of cerebral embolization. The echocardiogram demonstrated thickened mitral and aortic valves as potential sources of emboli. We conclude that ischemic stroke secondary to cardioembolization is a potential complication of Hunter syndrome.
MeSH terms
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Adult
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Anticoagulants / therapeutic use
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Brain / blood supply
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Brain / pathology
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Brain / physiopathology
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Brain Ischemia / diagnosis
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Brain Ischemia / etiology*
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Brain Ischemia / physiopathology
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Cerebral Infarction / diagnosis
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Cerebral Infarction / etiology*
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Cerebral Infarction / physiopathology
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Cerebral Veins / abnormalities
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Cerebral Veins / physiopathology
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Echocardiography
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Heart Valve Diseases / complications*
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Heart Valve Diseases / diagnosis
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Heart Valve Diseases / physiopathology
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Heart Valves / pathology
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Heart Valves / physiopathology
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Humans
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Infarction, Middle Cerebral Artery / diagnosis
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Infarction, Middle Cerebral Artery / etiology
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Infarction, Middle Cerebral Artery / physiopathology
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Intracranial Embolism / diagnosis
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Intracranial Embolism / etiology*
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Intracranial Embolism / physiopathology
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Intracranial Hypertension / etiology
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Intracranial Hypertension / physiopathology
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Male
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Middle Cerebral Artery / diagnostic imaging
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Middle Cerebral Artery / pathology
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Middle Cerebral Artery / physiopathology
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Mucopolysaccharidosis II / complications*
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Mucopolysaccharidosis II / physiopathology
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Tomography, X-Ray Computed
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Treatment Outcome