Differences in adherence and motivation to HIV therapy--two independent assessments in 1998 and 2002

Pharm World Sci. 2006 Aug;28(4):248-56. doi: 10.1007/s11096-006-9036-4. Epub 2006 Oct 26.

Abstract

Objective: The aim of this study was to compare the level of adherence and motivation in two independent cross-sectional samples of HIV-infected patients conducted in 1998 and 2002, and to investigate the relationship between adherence and motivation.

Method: Consecutive HIV-infected patients on treatment at a Swedish clinic were asked to complete an anonymous questionnaire. In 1998, 60 patients participated and in 2002, 53 participated. In 2002, the 9-item Morisky Medication Adherence Scale (MMAS) was added to the questionnaire set.

Main outcome measure: Self-reported adherence and motivation.

Results: In 1998, 28.1% of the respondents were considered adherent, while the corresponding proportion was 57.4% in 2002 (P = 0.002). The mean summary score for MMAS was 10.7 in 2002 (13 = perfect adherence). The proportion considered motivated were 22.4% in the 1998 survey and 41.3% in 2002 (P = 0.038). Of the respondents considered motivated in the 2002 survey, 46.7% scored the maximum summary score on the MMAS, while 8.7% of the non-motivated respondents did so (P = 0.016).

Conclusion: The respondents in 2002 were more adherent and motivated than the respondents in 1998 and a relationship between motivation and adherence was found. The difference in adherence and motivation might be due to a new treatment model at the clinic.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anti-HIV Agents / therapeutic use*
  • Attitude to Health
  • Cross-Sectional Studies
  • Female
  • HIV Infections / drug therapy*
  • HIV Infections / psychology
  • Hospitals, University
  • Humans
  • Male
  • Motivation*
  • Outpatients / psychology
  • Outpatients / statistics & numerical data
  • Patient Compliance / statistics & numerical data*
  • Program Evaluation / methods
  • Reproducibility of Results
  • Surveys and Questionnaires*
  • Sweden
  • Time Factors

Substances

  • Anti-HIV Agents