Virtual screening for PPAR modulators using a probabilistic neural network

ChemMedChem. 2006 Dec;1(12):1346-50. doi: 10.1002/cmdc.200600166.

Authors

Swetlana Derksen¹, Oliver Rau, Petra Schneider, Manfred Schubert-Zsilavecz, Gisbert Schneider

Affiliation

¹ Johann Wolfgang Goethe University, Institute of Organic Chemistry and Chemical Biology/ZAFES, Siesmayerstrasse 70, 60323 Frankfurt/Main, Germany.

PMID: 17066499
DOI: 10.1002/cmdc.200600166

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
COS Cells
Chlorocebus aethiops
Drug Design
Hypoglycemic Agents / chemistry*
Hypoglycemic Agents / pharmacology*
Ligands
Molecular Structure
Neural Networks, Computer*
Peroxisome Proliferator-Activated Receptors / chemistry*
Peroxisome Proliferator-Activated Receptors / drug effects*
Probability
Protein Conformation
Protein Structure, Secondary
Sensitivity and Specificity
Structure-Activity Relationship

Substances

Hypoglycemic Agents
Ligands
Peroxisome Proliferator-Activated Receptors