Identification of several proteins involved in regulation of sperm motility by proteomic analysis

Chun Zhao; Ran Huo; Fu-Qiang Wang; Min Lin; Zuo-Min Zhou; Jia-Hao Sha

doi:10.1016/j.fertnstert.2006.06.057

Identification of several proteins involved in regulation of sperm motility by proteomic analysis

Fertil Steril. 2007 Feb;87(2):436-8. doi: 10.1016/j.fertnstert.2006.06.057. Epub 2006 Oct 30.

Authors

Chun Zhao¹, Ran Huo, Fu-Qiang Wang, Min Lin, Zuo-Min Zhou, Jia-Hao Sha

Affiliation

¹ Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing, People's Republic of China.

PMID: 17074334
DOI: 10.1016/j.fertnstert.2006.06.057

Abstract

Proteomic technology was used to compare sperm protein expression profiles in asthenozoospermic patients with that of normozoospermic donors and 10 differentially expressed proteins were identified. These proteins may play roles in the regulation of sperm motility, and their characterization could merit further investigation on sperm motility-related male factor infertility.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Asthenozoospermia / metabolism*
Gene Expression Profiling*
Humans
Infertility, Male / metabolism*
Male
Proteome / metabolism*
Sperm Motility*
Spermatozoa / metabolism*

Substances

Proteome