Loss of the BH3-only protein Bid does not rescue RelA-deficient embryos from TNF-R1-mediated fatal hepatocyte destruction

Cell Death Differ. 2007 Mar;14(3):637-9. doi: 10.1038/sj.cdd.4402061. Epub 2006 Nov 10.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Apoptosis
  • BH3 Interacting Domain Death Agonist Protein / genetics
  • BH3 Interacting Domain Death Agonist Protein / metabolism*
  • Hepatocytes / metabolism
  • Hepatocytes / physiology*
  • Mice
  • Mice, Knockout
  • Peptide Fragments / genetics
  • Peptide Fragments / metabolism*
  • Proto-Oncogene Proteins / genetics
  • Proto-Oncogene Proteins / metabolism*
  • Receptors, Tumor Necrosis Factor, Type I / metabolism
  • Signal Transduction
  • Transcription Factor RelA / genetics
  • Transcription Factor RelA / metabolism*
  • Tumor Necrosis Factors / pharmacology

Substances

  • BH3 Interacting Domain Death Agonist Protein
  • Bax protein (53-86)
  • Peptide Fragments
  • Proto-Oncogene Proteins
  • Receptors, Tumor Necrosis Factor, Type I
  • Transcription Factor RelA
  • Tumor Necrosis Factors