Fluorescently tagged polymer bioconjugates from protein derived macroinitiators

Chem Commun (Camb). 2006 Dec 7:(45):4697-9. doi: 10.1039/b609935a. Epub 2006 Sep 29.

Abstract

BSA and lysozyme have been transformed into macroinitiators for living radical polymerisation and used to produce well-defined bioconjugates which can be fluorescently labelled providing a versatile strategy for the preparation of bioconjugates which is complementary to traditional PEGylation.

MeSH terms

  • Animals
  • Biopolymers / chemistry
  • Cattle
  • Chromatography, High Pressure Liquid
  • Electrophoresis, Polyacrylamide Gel
  • Fluorescent Dyes / chemistry*
  • Heterocyclic Compounds, 4 or More Rings / chemistry*
  • Molecular Structure
  • Muramidase / chemistry*
  • Polyethylene Glycols / chemistry*
  • Rhodamines / chemistry*
  • Serum Albumin, Bovine / chemistry*

Substances

  • Biopolymers
  • Fluorescent Dyes
  • Heterocyclic Compounds, 4 or More Rings
  • Rhodamines
  • hostasol
  • Serum Albumin, Bovine
  • Polyethylene Glycols
  • Muramidase
  • rhodamine B