Abstract
The article is dedicated to bacterial translocation under the conditions of acute small and large bowel obstruction, studied in experiment using bacteriological methods. The degree of contamination of internal organs, blood, and peritoneal exudate in the dynamics of the pathological process was determined. The study found that the use of allopurinol, a xanthine oxidase inhibitor, reduced the intensity of bacterial translocation.
Publication types
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Comparative Study
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English Abstract
MeSH terms
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Acute Disease
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Allopurinol / administration & dosage
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Allopurinol / pharmacology
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Animals
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Ascitic Fluid / microbiology*
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Bacterial Translocation* / drug effects
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Bacteriological Techniques
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Blood / microbiology*
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Enzyme Inhibitors / administration & dosage
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Enzyme Inhibitors / pharmacology
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Female
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Intestinal Mucosa / microbiology
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Intestinal Obstruction / microbiology*
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Intestine, Large / microbiology
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Intestine, Small / microbiology
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Liver / microbiology*
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Lung / microbiology*
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Male
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Rabbits
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Spleen / microbiology*
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Time Factors
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Xanthine Oxidase / antagonists & inhibitors
Substances
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Enzyme Inhibitors
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Allopurinol
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Xanthine Oxidase