Unexpected formation of hydroxybiphenylmethane derivatives and some new observations on Labat test

Nat Prod Res. 2006 Oct;20(12):1150-4. doi: 10.1080/14786410600917902.

Abstract

An unexpected synthesis of symmetrical hydroxybiphenylmethanes involving the reaction of 2-hydroxyphenyl benzyl ketones with ethoxymethyl chloride has been observed. Some new interesting observations of Labat test on colorimetric detection of bichalconyloxy, bichalconyl and biflavonylmethanes having oxygenated ortho positions are presented.

MeSH terms

  • Biphenyl Compounds / chemical synthesis*
  • Chemistry Techniques, Analytical / methods*
  • Colorimetry
  • Flavanones / chemical synthesis*
  • Gallic Acid
  • Ketones / chemistry
  • Magnetic Resonance Spectroscopy
  • Methyl Chloride / chemistry
  • Molecular Structure

Substances

  • Biphenyl Compounds
  • Flavanones
  • Ketones
  • Gallic Acid
  • Methyl Chloride