Pregnancy and birth outcomes in women with facioscapulohumeral muscular dystrophy

Neurology. 2006 Nov 28;67(10):1887-9. doi: 10.1212/01.wnl.0000244471.05316.19.

Abstract

Obstetric risk in facioscapulohumeral muscular dystrophy (FSHD) is not known. We surveyed 38 women with FSHD reporting 105 gestations and 78 live births. Review of medical records showed that pregnancy outcomes were generally favorable. The rates for low birth weight and total operative deliveries were statistically higher than the national rates in the general population. Worsening of FSHD was reported in 24% of gestations and did not usually resolve after delivery.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Birth Injuries / epidemiology*
  • Cesarean Section / statistics & numerical data
  • Comorbidity
  • Cross-Sectional Studies
  • Disease Progression
  • Female
  • Fetal Distress / epidemiology
  • Humans
  • Infant, Low Birth Weight / physiology
  • Infant, Newborn
  • Infections / epidemiology
  • Muscle Weakness / epidemiology
  • Muscular Dystrophy, Facioscapulohumeral / epidemiology*
  • Pregnancy
  • Pregnancy Complications / epidemiology*
  • Surveys and Questionnaires