[French survey about intradermal BCG SSI adverse events in children under 6 years of age]

Arch Pediatr. 2007 Jan;14(1):102-8. doi: 10.1016/j.arcped.2006.10.005. Epub 2006 Nov 30.
[Article in French]

Abstract

During April 2006, 579 physicians took part in a survey about intradermal BCG SSI adverse events (AE) in children less than 6 years old, managed by InfoVac France. Since January 2006, 68% physicians (paediatricians: 73% and general practitioners [GP]: 60%) have vaccinated at least one child. The site of injection is mainly the extern side of the shoulder (72%), according to the recommendations. Systematic vaccination is continued by 54% GP and 26% paediatricians. Others indications are: admission in day care center (33%), admission in day care center associated with risk factors (24%), or only risks factors (8%). Half physicians observed AE and 6% of them reported them at pharmacovigilance centers or pharmaceutical company. AE were mainly inflammations or indurations over 1 cm (for 75% of physicians who observed AE), oozing (73%). Abscesses are notified by 54%, ulcers by 39%, lymphadenopathies over 1 cm by 20%, suppurative lymphadenopathies by 3% and keloid scares by 17% of them, several AE may coexist for some children. Our aim is to start a prospective follow-up of BCG-SSI vaccination and its AE; 58% physicians who answered this investigation agreed to participate.

Publication types

  • English Abstract

MeSH terms

  • Adverse Drug Reaction Reporting Systems*
  • BCG Vaccine / administration & dosage
  • BCG Vaccine / adverse effects*
  • Child
  • Child, Preschool
  • France
  • Humans
  • Injections, Intradermal
  • Retrospective Studies
  • Surveys and Questionnaires

Substances

  • BCG Vaccine