Effect of warm ischemia on graft outcome in laparoscopic donor nephrectomy

J Endourol. 2006 Nov;20(11):895-8. doi: 10.1089/end.2006.20.895.

Abstract

Purpose: To assess the impact of warm ischemia time (WIT) on delayed graft function (DGF), graft loss, and graft function in laparoscopic donor nephrectomy (LDN).

Patients and methods: We prospectively studied 100 kidney recipients from LDN donors from 2001 to 2003. For comparison of graft outcome with different extents of WIT, recipients were divided into three groups: group A received kidneys having 4 to 6 minutes, group B kidneys having >6 to 10 minutes, and group C kidneys having >10 minutes of WIT. The median follow-up was 415 days (range 11-791) days.

Results: The mean kidney WIT was 8.7 minutes (range 4-17 minutes). Graft outcome (DGF, graft loss, and median serum creatinine) was not significantly different in the three groups.

Conclusions: Different extents of WIT in LDN, within the range of our study, were not associated with an adverse outcome in kidney transplantation.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Follow-Up Studies
  • Graft Survival*
  • Humans
  • Kidney Transplantation*
  • Laparoscopy
  • Living Donors*
  • Male
  • Middle Aged
  • Nephrectomy
  • Prospective Studies
  • Time Factors
  • Warm Ischemia* / adverse effects