Chronic clinical manifestations related to Wuchereria bancrofti infection in a highly endemic area in Kenya

Trans R Soc Trop Med Hyg. 2007 May;101(5):439-44. doi: 10.1016/j.trstmh.2006.09.006. Epub 2006 Dec 4.

Abstract

Clinical examinations were conducted in an effort to provide baseline data for a pilot filariasis elimination programme implemented in a Wuchereria bancrofti-endemic focus in Malindi district, Kenya. Of 186 males aged 15 years and above examined, 64 individuals (34.4%) had hydrocele, and the prevalence of the manifestation in those above 40 years old was 55.3%. The prevalence of leg lymphoedema in persons aged 15 years and above was 8.5%, with a higher rate in males (12.6%) than in females (5.7%). The overall prevalence of inguinal adenopathy was 8.6%, and males had a significantly higher (12.9%) prevalence of adenopathy than females (5.1%) (P<0.001). The data in the present study provided support for consideration of filarial infection as a possible cause of inguinal lymphadenopathy in bancroftian filariasis-endemic areas. The results of this study also indicate that lymphatic filariasis is a serious public health problem in the northern coastal areas and morbidity control programmes should be implemented to alleviate the suffering of those affected.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Animals
  • Chronic Disease
  • Elephantiasis, Filarial / complications*
  • Elephantiasis, Filarial / epidemiology
  • Endemic Diseases
  • Female
  • Humans
  • Inguinal Canal
  • Kenya / epidemiology
  • Leg
  • Lymphatic Diseases / parasitology
  • Lymphedema / parasitology*
  • Male
  • Testicular Hydrocele / parasitology*
  • Wuchereria bancrofti*