Abstract
Microwave assisted indirect functionalization of alcohols with 1,3-dimethylbarbituric acid followed by spirocyclisation employing a sequential one-pot Ir(III)/Pd(0) catalysed process, involving the formation of three new C-C bonds, one spirocyclic ring and one di- or tri-substituted exocyclic alkene, is described.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkadienes / chemistry*
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Alkylation
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Barbiturates / chemical synthesis*
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Barbiturates / chemistry
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Benzyl Alcohols / chemistry
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Catalysis
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Crystallography, X-Ray
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Cyclization
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Heterocyclic Compounds / chemical synthesis
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Heterocyclic Compounds / chemistry
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Iridium / chemistry*
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Microwaves
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Models, Molecular
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Molecular Conformation
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Molecular Structure
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Palladium / chemistry*
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Spiro Compounds / chemical synthesis
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Spiro Compounds / chemistry
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Stereoisomerism
Substances
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Alkadienes
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Barbiturates
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Benzyl Alcohols
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Heterocyclic Compounds
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Spiro Compounds
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Iridium
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propadiene
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Palladium
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1,3-dimethylbarbituric acid