Immunoasssay based on the antibody-conjugated PAMAM-dendrimer-gold quantum dot complex

Chem Commun (Camb). 2006 Dec 28:(48):5068-70. doi: 10.1039/b611278a. Epub 2006 Nov 21.

Abstract

An immunoassay based upon photoluminescent gold quantum dots aimed at detecting human IgG in aqueous solution from micromolar to nanomolar concentrations is described.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Antibodies / analysis
  • Antibodies / chemistry*
  • Antibodies / immunology
  • Dendrimers
  • Fluorescent Antibody Technique, Direct / methods
  • Goats
  • Gold / chemistry*
  • Humans
  • Immunoassay / methods
  • Immunoglobulin G / analysis
  • Immunoglobulin G / immunology
  • Microscopy, Atomic Force
  • Microscopy, Electron, Transmission
  • Polyamines / chemistry*
  • Quantum Dots*
  • Spectrometry, Fluorescence
  • Spectrophotometry, Ultraviolet

Substances

  • Antibodies
  • Dendrimers
  • Immunoglobulin G
  • PAMAM Starburst
  • Polyamines
  • Gold