Efficacy of a behavioral intervention for increasing safer sex behaviors in HIV-positive MSM methamphetamine users: results from the EDGE study

Drug Alcohol Depend. 2007 Mar 16;87(2-3):249-57. doi: 10.1016/j.drugalcdep.2006.08.026. Epub 2006 Dec 19.

Abstract

Background: Methamphetamine use has been associated with rising STI/HIV transmission rates, particularly among men who have sex with men (MSM). Interventions which successfully reduce risk for HIV transmission among this population are a public health priority. This study examined the efficacy of a behavioral intervention for increasing safer sex behaviors in the context of ongoing methamphetamine use in a sample of HIV-positive, methamphetamine-using MSM.

Methods: Three-hundred and forty-one participants from San Diego, CA were randomly assigned to receive either a safer sex behavioral intervention (EDGE) or a time-equivalent diet-and-exercise attention-control condition. Random effects regression analyses were used to evaluate change in safer sex behaviors over a 12-month period.

Results: Participants in the EDGE intervention engaged in significantly more protected sex acts at the 8-month (p=0.034) and 12-month assessment (p=0.007). By 12-months post-baseline, a greater percentage of protected sex acts was observed for EDGE (25.8%) vs. control participants (18.7%) (p=0.038). There was a significant time-by-intervention interaction (p=0.018) for self-efficacy for condom use, suggesting that EDGE participants' self-efficacy demonstrated a greater increase over time compared to control participants.

Conclusions: These results suggest that it is possible to reduce high risk sexual behaviors in the context of ongoing methamphetamine use among HIV-infected MSM.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Attention
  • Condoms
  • Depression / epidemiology
  • Diet
  • Exercise
  • Female
  • Follow-Up Studies
  • HIV Infections / prevention & control
  • HIV Infections / transmission
  • HIV Seropositivity / complications
  • HIV Seropositivity / psychology*
  • Homosexuality / statistics & numerical data*
  • Humans
  • Male
  • Methamphetamine*
  • Safe Sex / psychology*
  • Self Efficacy
  • Sex Education*
  • Sexual Behavior
  • Socioeconomic Factors
  • Substance-Related Disorders / complications
  • Substance-Related Disorders / psychology*

Substances

  • Methamphetamine