Hybridization of mouse leukemia virus c-DNA to mouse repeated DNA sequences

Acta Haematol. 1975;54(4):221-6. doi: 10.1159/000208078.

Abstract

Experiments of hybridization between mouse leukemia virus synthetic 3H-DNA probe and mouse main band and satellite DNAs indicate that there is not a higher concentration of viral sequences in the satellite DNA. On the contrary, viral sequences appear to be enriched in the fast renaturing intermediate main band DNA.

MeSH terms

  • Animals
  • Base Sequence
  • Cell Line
  • Cell Transformation, Neoplastic
  • DNA, Satellite / metabolism
  • DNA, Single-Stranded
  • DNA, Viral / metabolism*
  • Leukemia Virus, Murine / metabolism*
  • Mice
  • Mice, Inbred Strains
  • Nucleic Acid Conformation
  • Nucleic Acid Denaturation
  • Nucleic Acid Hybridization*
  • Nucleic Acid Renaturation
  • Ultracentrifugation

Substances

  • DNA, Satellite
  • DNA, Single-Stranded
  • DNA, Viral