Fusion of H4/D10S170 to PDGFRbeta in a patient with chronic myelomonocytic leukemia and long-term responsiveness to imatinib

Ann Hematol. 2007 May;86(5):353-4. doi: 10.1007/s00277-006-0247-5. Epub 2007 Jan 9.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Benzamides
  • Cytoskeletal Proteins / genetics
  • Gene Fusion / drug effects*
  • Humans
  • Imatinib Mesylate
  • Leukemia, Myelomonocytic, Chronic / drug therapy*
  • Leukemia, Myelomonocytic, Chronic / genetics*
  • Mutant Chimeric Proteins / analysis
  • Mutant Chimeric Proteins / drug effects
  • Mutant Chimeric Proteins / genetics*
  • Piperazines / pharmacology*
  • Piperazines / therapeutic use
  • Protein Kinase Inhibitors / pharmacology*
  • Protein Kinase Inhibitors / therapeutic use
  • Pyrimidines / pharmacology*
  • Pyrimidines / therapeutic use
  • Receptor, Platelet-Derived Growth Factor beta / genetics
  • Translocation, Genetic / drug effects

Substances

  • Benzamides
  • CCDC6 protein, human
  • Cytoskeletal Proteins
  • Mutant Chimeric Proteins
  • Piperazines
  • Protein Kinase Inhibitors
  • Pyrimidines
  • Imatinib Mesylate
  • Receptor, Platelet-Derived Growth Factor beta