Synthetic mimetics of the CD4 binding site of HIV-1 gp120 for the design of immunogens

Angew Chem Int Ed Engl. 2007;46(8):1253-5. doi: 10.1002/anie.200603274.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Antibodies, Monoclonal / immunology
  • Binding Sites
  • Biomimetic Materials / chemical synthesis*
  • Biomimetic Materials / chemistry
  • Biomimetic Materials / metabolism*
  • CD4 Antigens / chemistry
  • CD4 Antigens / metabolism*
  • Crystallography, X-Ray
  • Drug Design*
  • HIV Envelope Protein gp120 / chemistry*
  • HIV Envelope Protein gp120 / immunology*
  • HIV Envelope Protein gp120 / metabolism
  • Inhibitory Concentration 50
  • Models, Molecular
  • Molecular Sequence Data
  • Protein Structure, Quaternary

Substances

  • Antibodies, Monoclonal
  • CD4 Antigens
  • HIV Envelope Protein gp120