Translational repression of E2F1 mRNA in carcinoma in situ and normal testis correlates with expression of the miR-17-92 cluster

Cell Death Differ. 2007 Apr;14(4):879-82. doi: 10.1038/sj.cdd.4402090. Epub 2007 Jan 12.

Authors

G W Novotny, S B Sonne, J E Nielsen, S P Jonstrup, M A Hansen, N E Skakkebaek, E Rajpert-De Meyts, J Kjems, H Leffers

PMID: 17218954
DOI: 10.1038/sj.cdd.4402090

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Carcinoma in Situ / genetics*
Carcinoma in Situ / metabolism
Carcinoma in Situ / pathology
Carcinoma in Situ / ultrastructure*
Cell Cycle Proteins / biosynthesis*
E2F1 Transcription Factor / biosynthesis*
E2F1 Transcription Factor / genetics
Gene Expression Regulation / genetics
Germ Cells / metabolism
Germ Cells / ultrastructure*
Humans
Immunohistochemistry
In Situ Hybridization
Male
Mice
MicroRNAs / biosynthesis*
MicroRNAs / genetics
Protein Biosynthesis / genetics
RNA Processing, Post-Transcriptional / genetics
RNA, Messenger / biosynthesis*
RNA, Messenger / genetics
Testis / cytology
Testis / metabolism
Testis / ultrastructure

Substances

Cell Cycle Proteins
E2F1 Transcription Factor
E2F1 protein, human
MicroRNAs
RNA, Messenger