Abstract
This paper is a memorial to Mikhail Victorovich Berezkin (MVB) (10 April 1940 - 16 January 2005), an enthusiastic advocate of chrono-oncology. It illustrates his early dose- and circadian time-response curves, limited as yet by a 4-timepoint approach, provides a list of his publications, and offers a succinct overview of individualized marker rhythm-guided oncotherapy.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Animals
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Chronobiology Phenomena
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Chronotherapy / methods*
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Circadian Rhythm*
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Cyclophosphamide / administration & dosage*
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Disease-Free Survival
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Dose-Response Relationship, Drug
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Humans
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Mice
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Temperature
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Time Factors
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Vincristine / administration & dosage*
Substances
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Vincristine
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Cyclophosphamide