[A case of intravascular lymphomatosis with no abnormal findings on chest computed tomography and with diffuse pulmonary uptake of 67Ga on scintigraphy]

Nihon Kokyuki Gakkai Zasshi. 2006 Dec;44(12):923-7.
[Article in Japanese]

Abstract

A 45-year-old man was admitted to our hospital with high-grade fever uncontrolled by antipyretic drugs, and elevation of the serum LDH and sIL-2R levels, and decrease of diffusing capacity for carbon monoxide. Chest computed tomography (CT) showed no abnormal findings but 67Ga scintigraphy revealed diffuse pulmonary uptake. He was given a diagnosis of intravascular lymphomatosis (IVL) based on transbronchial lung biopsy (TBLB) and immunohistochemical analysis. The prognosis of IVL is generally bad, because antemortem diagnosis is difficult. In this case early TBLB enabled satisfactory curative effect of IVL.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / administration & dosage
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biopsy
  • Carbon Monoxide / metabolism
  • Cyclophosphamide / administration & dosage
  • Doxorubicin / administration & dosage
  • Drug Administration Schedule
  • Gallium Radioisotopes*
  • Humans
  • Lung / pathology
  • Lung Neoplasms / diagnostic imaging*
  • Lung Neoplasms / drug therapy
  • Lymphoma, B-Cell / diagnostic imaging*
  • Lymphoma, B-Cell / drug therapy
  • Lymphoma, Large B-Cell, Diffuse / diagnostic imaging*
  • Lymphoma, Large B-Cell, Diffuse / drug therapy
  • Male
  • Middle Aged
  • Prednisone / administration & dosage
  • Pulmonary Diffusing Capacity
  • Radiography, Thoracic
  • Radionuclide Imaging
  • Tomography, X-Ray Computed
  • Vascular Neoplasms / diagnostic imaging*
  • Vascular Neoplasms / drug therapy
  • Vincristine / administration & dosage

Substances

  • Gallium Radioisotopes
  • Vincristine
  • Carbon Monoxide
  • Doxorubicin
  • Cyclophosphamide
  • Prednisone

Supplementary concepts

  • CHOP protocol