Antigenic analysis of recent H1N1 influenza viruses with monoclonal antibodies

A Yamada; M S Cao; J Imanishi; S Oyama; A Abe; S Katagiri

Antigenic analysis of recent H1N1 influenza viruses with monoclonal antibodies

Acta Virol. 1991 Aug;35(4):343-9.

Authors

A Yamada¹, M S Cao, J Imanishi, S Oyama, A Abe, S Katagiri

Affiliation

¹ Department of Microbiology, Kyoto Prefectural University of Medicine, Japan.

PMID: 1724874

Abstract

Antigenic analysis of recently isolated H1 influenza viruses was performed using haemagglutination inhibition (HI) assay with monoclonal antibodies to the haemagglutinin (HA) subunit. Tests using monoclonal antibodies against the HA of the A/England/333/80 (H1N1) and A/Yamagata/120/86 (H1N1) viruses revealed that the major antigenic drift occurred in 1985 or 1986 and A/Dunedin/6/83-like virus became a major strain after 1986.

Publication types

Comparative Study

MeSH terms

Antibodies, Monoclonal / immunology*
Antibodies, Viral / immunology*
Antigenic Variation
Antigens, Viral / immunology*
Epitopes / immunology
Hemagglutination Inhibition Tests
Hemagglutinin Glycoproteins, Influenza Virus
Hemagglutinins, Viral / immunology*
Influenza A Virus, H1N1 Subtype*
Influenza A virus / immunology*

Substances

Antibodies, Monoclonal
Antibodies, Viral
Antigens, Viral
Epitopes
Hemagglutinin Glycoproteins, Influenza Virus
Hemagglutinins, Viral