Abstract
The objective of this study was to identify prognostic factors of death in patients with tuberculous meningitis (TM) and show the impact of infection by multidrug-resistant strains on the outcome of this disease. We retrospectively analysed clinical charts of HIV-infected patients with culture-confirmed TM attending our institution during 1996-2004. The following variables were associated with death during hospitalization: neurological signs at admission, a CD4 T-cell count less than 50 cells/microl and infection by multidrug-resistant strains.
MeSH terms
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AIDS-Related Opportunistic Infections / drug therapy*
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AIDS-Related Opportunistic Infections / immunology
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AIDS-Related Opportunistic Infections / microbiology
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Adult
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Antitubercular Agents / therapeutic use*
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Female
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Humans
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Male
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Prognosis
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Retrospective Studies
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Treatment Outcome
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Tuberculosis, Meningeal / drug therapy*
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Tuberculosis, Meningeal / immunology
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Tuberculosis, Meningeal / microbiology
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Tuberculosis, Multidrug-Resistant / drug therapy*
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Tuberculosis, Multidrug-Resistant / immunology
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Tuberculosis, Multidrug-Resistant / microbiology