[Mechanisms responsible for antitumor activity of melanoma differentiation-associated gene -7/interleukin-24]

Min Yang; Wen-Bin Qian

doi:10.3785/j.issn.1008-9292.2007.01.017

[Mechanisms responsible for antitumor activity of melanoma differentiation-associated gene -7/interleukin-24]

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2007 Jan;36(1):98-102. doi: 10.3785/j.issn.1008-9292.2007.01.017.

[Article in Chinese]

Authors

Min Yang¹, Wen-Bin Qian

Affiliation

¹ The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310003, China.

PMID: 17290500
DOI: 10.3785/j.issn.1008-9292.2007.01.017

Abstract

The melanoma differentiation-associated gene-7/interleukin-24 (MDA-7/IL-24) is a novel candidate of tumor suppressor, which can experimentally inhibit the proliferation of cancer cells and induce apoptosis of various human malignant cells.

Publication types

English Abstract
Research Support, Non-U.S. Gov't
Review

MeSH terms

Apoptosis
Cell Proliferation
Genetic Therapy / methods*
Humans
Interleukins / biosynthesis
Interleukins / genetics*
Neoplasms / metabolism
Neoplasms / pathology
Neoplasms / therapy*
Tumor Suppressor Proteins / biosynthesis
Tumor Suppressor Proteins / genetics*

Substances

Interleukins
Tumor Suppressor Proteins
interleukin-24