Concurrent infection with dengue virus type-2 and DENV-3 in a patient from Ceará, Brazil

Mem Inst Oswaldo Cruz. 2006 Dec;101(8):925-8. doi: 10.1590/s0074-02762006000800017.

Abstract

Dengue outbreaks have occurred in several regions in Brazil and cocirculating dengue virus type 1 (DENV-1), DENV-2, and DENV-3 have been frequently observed. Dual infection by DENV-2 and DENV-3 was identified by type-specific indirect immunofluorescence assay and confirmed by reverse transcription polymerase chain reaction in a patient in Ceará with a mild disease. This is the first documented case of simultaneous infection with DENV-2 and DENV-3 in Brazil. Sequencing confirmed DENV-2 and DENV-3 (South-East/American) genotype III and (SriLanka/India), genotype III respectively.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antibodies, Viral / blood
  • Brazil
  • Dengue / diagnosis
  • Dengue / virology*
  • Dengue Virus / classification*
  • Dengue Virus / genetics
  • Dengue Virus / immunology
  • Fluorescent Antibody Technique, Indirect
  • Genotype
  • Humans
  • Male
  • RNA, Viral / analysis
  • Reverse Transcriptase Polymerase Chain Reaction
  • Serotyping

Substances

  • Antibodies, Viral
  • RNA, Viral