Abstract
The most common renal manifestation of Sjögren's syndrome is tubulointerstitial nephritis, and glomerular disease is rare (3). A 62-year-old woman with primary Sjögren's syndrome developed nephrotic syndrome. Kidney biopsy was consistent with membraneous glomerulonephritis. Steroid pulse therapy was not effective. Three months later she was diagnosed with non-Hodgkin's lymphoma of the tongue, and she was given CHOP therapy and radiation. Both the lymphoma and membraneous glomerulonephritis were resolved.
MeSH terms
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Biopsy, Needle
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Combined Modality Therapy
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Female
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Follow-Up Studies
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Glomerulonephritis, Membranous / complications
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Glomerulonephritis, Membranous / diagnosis*
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Glomerulonephritis, Membranous / therapy
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Humans
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Immunohistochemistry
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Kidney Function Tests
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Lymphoma, Non-Hodgkin / complications
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Lymphoma, Non-Hodgkin / diagnosis*
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Lymphoma, Non-Hodgkin / therapy
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Middle Aged
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Paraneoplastic Syndromes / complications
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Paraneoplastic Syndromes / diagnosis*
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Paraneoplastic Syndromes / therapy
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Rare Diseases
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Severity of Illness Index
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Sjogren's Syndrome / complications
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Sjogren's Syndrome / diagnosis*
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Sjogren's Syndrome / therapy
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Treatment Outcome
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Urinalysis