A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome

Leukemia. 2007 Apr;21(4):830-3. doi: 10.1038/sj.leu.2404541. Epub 2007 Feb 15.

Authors

R La Starza, R Rosati, G Roti, P Gorello, A Bardi, B Crescenzi, V Pierini, O Calabrese, M Baens, C Folens, J Cools, P Marynen, M F Martelli, C Mecucci, A Cuneo

PMID: 17301821
DOI: 10.1038/sj.leu.2404541

No abstract available

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Base Sequence
Chromosomes, Human, Pair 16*
Chromosomes, Human, Pair 5*
Female
Gene Fusion*
Humans
In Situ Hybridization, Fluorescence
Leukemia, Myelomonocytic, Chronic / genetics*
Noonan Syndrome / genetics*
Receptor, Platelet-Derived Growth Factor beta / genetics*
Site-Specific DNA-Methyltransferase (Adenine-Specific) / genetics*
Transcription, Genetic*
Translocation, Genetic

Substances

DNA modification methylase NdeI
Site-Specific DNA-Methyltransferase (Adenine-Specific)
Receptor, Platelet-Derived Growth Factor beta