Hepatotoxicity due to a drug interaction between amodiaquine plus artesunate and efavirenz

Clin Infect Dis. 2007 Mar 15;44(6):889-91. doi: 10.1086/511882.
No abstract available

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Alkynes
  • Amodiaquine / adverse effects*
  • Amodiaquine / therapeutic use
  • Artemisinins / adverse effects*
  • Artemisinins / therapeutic use
  • Artesunate
  • Benzoxazines
  • Chemical and Drug Induced Liver Injury*
  • Cohort Studies
  • Cyclopropanes
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Drug Interactions
  • Drug Therapy, Combination
  • Female
  • Humans
  • Liver Diseases / enzymology
  • Liver Function Tests
  • Male
  • Middle Aged
  • Oxazines / adverse effects*
  • Oxazines / therapeutic use
  • Reference Values
  • Risk Assessment
  • Sesquiterpenes / adverse effects*
  • Sesquiterpenes / therapeutic use
  • Transaminases / blood

Substances

  • Alkynes
  • Artemisinins
  • Benzoxazines
  • Cyclopropanes
  • Oxazines
  • Sesquiterpenes
  • Amodiaquine
  • Artesunate
  • Transaminases
  • efavirenz