Otological toxicity after postoperative radiotherapy for parotid tumours

Clin Oncol (R Coll Radiol). 2007 Feb;19(1):77-82. doi: 10.1016/j.clon.2006.11.007.

Abstract

Radiotherapy is commonly used in the management of malignant parotid gland tumours that have adverse pathological risk factors after surgery. Radiation to the parotid bed is associated with predictable complications. In particular, the close proximity of the auditory apparatus, which receives a significant radiation dose, results in significant toxicity in a proportion of patients. Here we review auditory toxicity after radiation to the parotid bed.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / adverse effects
  • Combined Modality Therapy
  • Dose-Response Relationship, Radiation
  • Ear / radiation effects*
  • Hearing Loss, Sensorineural / etiology
  • Humans
  • Parotid Gland / radiation effects*
  • Parotid Neoplasms / drug therapy
  • Parotid Neoplasms / radiotherapy*
  • Parotid Neoplasms / surgery
  • Radiation Injuries / etiology*
  • Radiotherapy / adverse effects

Substances

  • Antineoplastic Agents