Abstract
MICs of tetracyclines were determined for 86 human Bifidobacterium isolates and three environmental strains. The tet(O) gene was found to be absent in these isolates. tet(W) and tet(M) were found in 26 and 7%, respectively, of the Bifidobacterium isolates, and one isolate contained both genes. Chromosomal DNA hybridization showed that there was one chromosomal copy of tet(W) and/or tet(M).
MeSH terms
-
Bacterial Proteins / genetics*
-
Bifidobacteriales Infections / microbiology*
-
Bifidobacterium / drug effects*
-
Bifidobacterium / genetics
-
Bifidobacterium / isolation & purification
-
Carrier Proteins / genetics*
-
Chromosomes, Bacterial / genetics
-
DNA, Bacterial / chemistry
-
DNA, Bacterial / genetics
-
Humans
-
Microbial Sensitivity Tests
-
Molecular Sequence Data
-
Nucleic Acid Hybridization
-
Sequence Analysis, DNA
-
Tetracycline Resistance / genetics*
Substances
-
Bacterial Proteins
-
Carrier Proteins
-
DNA, Bacterial
-
Tet M resistance protein, Bacteria
-
Tet O resistance protein, Bacteria
Associated data
-
GENBANK/DQ988352
-
GENBANK/DQ988353
-
GENBANK/DQ988354
-
GENBANK/DQ988355
-
GENBANK/DQ988356
-
GENBANK/DQ988357
-
GENBANK/DQ988358
-
GENBANK/DQ988359
-
GENBANK/DQ988360
-
GENBANK/DQ988361
-
GENBANK/DQ988362
-
GENBANK/DQ988363