Using singlet oxygen to synthesise a [6,6,5]-bis-spiroketal in one-pot from a simple 2,5-disubstituted furan

Maria Tofi; Tamsyn Montagnon; Thomas Georgiou; Georgios Vassilikogiannakis

doi:10.1039/b617966e

Using singlet oxygen to synthesise a [6,6,5]-bis-spiroketal in one-pot from a simple 2,5-disubstituted furan

Org Biomol Chem. 2007 Mar 7;5(5):772-7. doi: 10.1039/b617966e. Epub 2007 Jan 26.

Authors

Maria Tofi¹, Tamsyn Montagnon, Thomas Georgiou, Georgios Vassilikogiannakis

Affiliation

¹ Department of Chemistry, University of Crete, Vasilika Vouton, 71003 Iraklion, Crete, Greece.

PMID: 17315063
DOI: 10.1039/b617966e

Abstract

Singlet oxygen (1O2) proves to be a powerful tool in mediating the one-pot synthesis of a salinomycin-type [6,6,5]-bis-spiroketal unit starting from a suitably substituted furan nucleus.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Furans / chemistry*
Molecular Structure
Oxygen / chemistry*
Spiro Compounds / chemical synthesis*
Spiro Compounds / chemistry

Substances

Furans
Spiro Compounds
Oxygen