Systemic recombinant tissue plasminogen activator lysis for left atrial thrombus formation after single-lung retransplantation

Ann Thorac Surg. 1992 Feb;53(2):338-40. doi: 10.1016/0003-4975(92)91347-c.

Abstract

This report describes a recipient of single-lung transplantation surviving extraordinary complications: (1) early graft failure mandating retransplantation; (2) left atrial thrombus formation, which resolved by recombinant tissue plasminogen activator lysis; (3) and development of a "locked-in-syndrome." Possible underlying mechanisms are discussed.

Publication types

  • Case Reports

MeSH terms

  • Extracorporeal Membrane Oxygenation*
  • Female
  • Heart Atria
  • Heart Diseases / drug therapy*
  • Heart Diseases / etiology
  • Humans
  • Lung Transplantation / adverse effects*
  • Middle Aged
  • Pulmonary Fibrosis / surgery*
  • Quadriplegia / etiology
  • Reoperation
  • Thrombolytic Therapy*
  • Thrombosis / drug therapy*
  • Thrombosis / etiology
  • Tissue Plasminogen Activator / therapeutic use*

Substances

  • Tissue Plasminogen Activator