Control of hematopoiesis and apoptosis in MDS: more than FLIPing the coin

Leuk Res. 2007 Jun;31(6):747-9. doi: 10.1016/j.leukres.2007.01.010. Epub 2007 Feb 22.
No abstract available

Publication types

  • Comparative Study
  • Editorial
  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Antigens, Differentiation / biosynthesis
  • Antigens, Differentiation / genetics
  • Antineoplastic Agents / therapeutic use
  • Apoptosis* / drug effects
  • Apoptosis* / genetics
  • Azacitidine / therapeutic use
  • CASP8 and FADD-Like Apoptosis Regulating Protein / genetics
  • CASP8 and FADD-Like Apoptosis Regulating Protein / metabolism*
  • Caspase 8 / metabolism
  • Cell Differentiation / drug effects
  • Cell Differentiation / genetics
  • Endothelial Cells / metabolism
  • Endothelial Cells / pathology
  • Enzyme Inhibitors / therapeutic use
  • Gene Expression Regulation* / drug effects
  • Gene Expression Regulation* / genetics
  • Hematopoiesis* / drug effects
  • Hematopoiesis* / genetics
  • Hematopoietic Stem Cells / metabolism
  • Hematopoietic Stem Cells / pathology
  • Humans
  • Lenalidomide
  • Monocytes / metabolism
  • Monocytes / pathology
  • Myelodysplastic Syndromes / drug therapy
  • Myelodysplastic Syndromes / genetics
  • Myelodysplastic Syndromes / metabolism*
  • Myelodysplastic Syndromes / pathology
  • Signal Transduction* / drug effects
  • Signal Transduction* / genetics
  • Stromal Cells / metabolism
  • Stromal Cells / pathology
  • T-Lymphocytes / metabolism
  • T-Lymphocytes / pathology
  • Thalidomide / analogs & derivatives
  • Thalidomide / therapeutic use

Substances

  • Antigens, Differentiation
  • Antineoplastic Agents
  • CASP8 and FADD-Like Apoptosis Regulating Protein
  • Enzyme Inhibitors
  • Thalidomide
  • CASP8 protein, human
  • Caspase 8
  • Lenalidomide
  • Azacitidine