Lung premalignancy induced by mutant B-Raf, what is thy fate? To senesce or not to senesce, that is the question

Genes Dev. 2007 Feb 15;21(4):361-6. doi: 10.1101/gad.1532107.
No abstract available

Publication types

  • Comment

MeSH terms

  • Animals
  • Cellular Senescence / genetics
  • Humans
  • Lung Neoplasms / enzymology
  • Lung Neoplasms / genetics*
  • Lung Neoplasms / therapy
  • MAP Kinase Kinase Kinases / antagonists & inhibitors
  • MAP Kinase Kinase Kinases / metabolism
  • Mice
  • Mutation
  • Phosphatidylinositol 3-Kinases / metabolism
  • Precancerous Conditions / enzymology
  • Precancerous Conditions / genetics*
  • Precancerous Conditions / therapy
  • Proto-Oncogene Proteins B-raf / genetics*
  • Proto-Oncogene Proteins B-raf / physiology

Substances

  • Phosphatidylinositol 3-Kinases
  • BRAF protein, human
  • Braf protein, mouse
  • Proto-Oncogene Proteins B-raf
  • MAP Kinase Kinase Kinases