Mutagenic, antimutagenic and antioxidant activities of a new class of beta-glucoside hydroxyhydroquinone from Anagallis monelli growing in Tunisia

Chem Pharm Bull (Tokyo). 2007 Mar;55(3):385-8. doi: 10.1248/cpb.55.385.

Abstract

A new skeleton of an O-heteroside natural substance named zinolol, the first representative of a new class of aminated hydroxyhydroquinone, has been isolated from the whole plant Anagallis monelli. Its structure has been established by one and two dimensional NMR spectroscopic procedures. Antioxidant, mutagenic, antimutagenic activities were realised and positive results were recorded.

MeSH terms

  • Anagallis / chemistry*
  • Antioxidants / chemistry
  • Antioxidants / pharmacology
  • Biphenyl Compounds / chemistry
  • Escherichia coli / drug effects
  • Escherichia coli / genetics
  • Free Radical Scavengers / chemistry
  • Free Radical Scavengers / pharmacology
  • Glucosides / chemistry*
  • Glucosides / pharmacology*
  • Hydrazines / chemistry
  • Hydroquinones / chemistry*
  • Hydroquinones / pharmacology*
  • Molecular Structure
  • Mutagenicity Tests
  • Picrates
  • Tunisia

Substances

  • Antioxidants
  • Biphenyl Compounds
  • Free Radical Scavengers
  • Glucosides
  • Hydrazines
  • Hydroquinones
  • Picrates
  • zinolol
  • hydroxyhydroquinone
  • 1,1-diphenyl-2-picrylhydrazyl