Immune reconstitution sarcoidosis presenting with hypercalcaemia and renal failure in HIV infection

R A Ferrand; J D Cartledge; J Connolly; R A Standish; R F Miller

doi:10.1258/095646207779949574

Immune reconstitution sarcoidosis presenting with hypercalcaemia and renal failure in HIV infection

Int J STD AIDS. 2007 Feb;18(2):138-9. doi: 10.1258/095646207779949574.

Authors

R A Ferrand¹, J D Cartledge, J Connolly, R A Standish, R F Miller

Affiliation

¹ University College London Hospitals, London NW1 2BU, UK; Camden Primary Care Trust, Mortimer Market Centre, London WC1E 6AU, UK.

PMID: 17331293
DOI: 10.1258/095646207779949574

Abstract

An HIV-positive white man developed hypercalcaemia and renal failure 15 months after starting highly active antiretroviral therapy. Investigations showed systemic sarcoidosis affecting parotids, skin and kidneys. This presentation was thought to be a manifestation of immune reconstitution inflammatory syndrome, and the patient was successfully treated with corticosteroid therapy.

Publication types

Case Reports

MeSH terms

AIDS-Related Opportunistic Infections / complications*
AIDS-Related Opportunistic Infections / drug therapy
AIDS-Related Opportunistic Infections / immunology
Adrenal Cortex Hormones / therapeutic use
Antiretroviral Therapy, Highly Active*
HIV Infections / complications
HIV Infections / drug therapy
HIV Infections / immunology*
Humans
Hypercalcemia / drug therapy
Hypercalcemia / etiology*
Male
Middle Aged
Renal Insufficiency / drug therapy
Renal Insufficiency / etiology*
Sarcoidosis / complications*
Sarcoidosis / drug therapy

Substances

Adrenal Cortex Hormones