Inflammatory pseudotumour of the paranasal sinuses--a case report

Auris Nasus Larynx. 2007 Dec;34(4):533-6. doi: 10.1016/j.anl.2007.01.003. Epub 2007 Feb 28.

Abstract

Inflammatory pseudotumour represents benign non-specific granulation, and is uncommon in the head-and-neck region, particularly in the paranasal sinuses. We present herein the case of a 63-year-old woman with inflammatory pseudotumour of the paranasal sinuses. Physical examination and computed tomography revealed a mass in the bilateral nasal cavity and paranasal sinuses with extension to bilateral orbits. Multiple intranasal biopsies revealed marked lymphoplasmatic infiltration and myofibroblastic proliferation with hyalinisation. Systemic steroid therapy was selected and was very effective. The lesion has shown no evidence of enlargement for more than 1 year. The difficulties in establishing the clinico-pathological diagnosis and treatment are discussed.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage
  • Biopsy
  • Diagnosis, Differential
  • Diplopia / etiology*
  • Disease Progression
  • Female
  • Granuloma, Plasma Cell / diagnosis*
  • Granuloma, Plasma Cell / drug therapy
  • Granuloma, Plasma Cell / pathology
  • Humans
  • Magnetic Resonance Imaging
  • Middle Aged
  • Neoplasm Invasiveness
  • Neoplasm Recurrence, Local / diagnosis*
  • Neoplasm Recurrence, Local / drug therapy
  • Neoplasm Recurrence, Local / pathology
  • Orbital Neoplasms / diagnosis*
  • Orbital Neoplasms / drug therapy
  • Orbital Neoplasms / pathology
  • Paranasal Sinus Diseases / diagnosis*
  • Paranasal Sinus Diseases / drug therapy
  • Paranasal Sinus Diseases / pathology
  • Paranasal Sinuses / pathology
  • Prednisolone / administration & dosage
  • Tomography, X-Ray Computed

Substances

  • Anti-Inflammatory Agents
  • Prednisolone