[Influence of percutaneous coronary intervention in non ST-elevation acute coronary syndromes on prescription of secondary prevention medications. Data from the S-Témoin Registry]

Ann Cardiol Angeiol (Paris). 2007 Jan;56(1):30-5. doi: 10.1016/j.ancard.2006.10.002.
[Article in French]

Abstract

Background: The interaction between the use of percutaneous coronary intervention (PCI) for non-ST-elevation acute coronary syndromes and the use of secondary prevention medications was analysed in the French S-Témoin Registry.

Methods: The population consisted of 2433 patients seen by their cardiologists at an outpatient clinic 2-12 months after non ST-elevation ACS; the survey was carried out from September 2004 to April 2005.

Results: Overall, patients undergoing PCI (75% of the population) had higher levels of prescription of recommended secondary prevention medications. Multivariate logistic regression analysis showed that the use and type of coronary intervention (drug eluting versus bare metal stents) was an independent correlate of the use of dual antiplatelet therapy. In addition, time from the acute episode was also a strong correlate of dual antiplatelet therapy. Statins were also more often used in patients with PCI.

Conclusion: Patients not treated with PCI are less likely to receive appropriate secondary prevention medications after non ST-elevation acute coronary syndromes. Specific efforts should be directed towards these patients, in particular as regards the prescription of dual antiplatelet therapy.

Publication types

  • English Abstract
  • Multicenter Study

MeSH terms

  • Adrenergic beta-Antagonists / therapeutic use
  • Aged
  • Angina, Unstable / prevention & control
  • Angina, Unstable / therapy
  • Angioplasty, Balloon, Coronary*
  • Calcium Channel Blockers / therapeutic use
  • Cardiovascular Agents / therapeutic use*
  • Chemoprevention
  • Drug Prescriptions
  • Female
  • Follow-Up Studies
  • France
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
  • Male
  • Middle Aged
  • Myocardial Infarction / prevention & control
  • Myocardial Infarction / therapy*
  • Platelet Aggregation Inhibitors / therapeutic use
  • Registries
  • Stents
  • Syndrome

Substances

  • Adrenergic beta-Antagonists
  • Calcium Channel Blockers
  • Cardiovascular Agents
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Platelet Aggregation Inhibitors