Segmentation of the surfaces of the retinal layer from OCT images

Med Image Comput Comput Assist Interv. 2006;9(Pt 1):800-7. doi: 10.1007/11866565_98.

Abstract

We have developed a method for the automated segmentation of the internal limiting membrane and the pigment epithelium in 3-D OCT retinal images. Each surface was found as a minimum s-t cut from a geometric graph constructed from edge/regional information and a priori-determined surface constraints. Our approach was tested on 18 3-D data sets (9 from patients with normal optic discs and 9 from patients with papilledema) obtained using a Stratus OCT-3 scanner. Qualitative analysis of surface detection correctness indicates that our method consistently found the correct surfaces and outperformed the proprietary algorithm used in the Stratus OCT-3 scanner. For example, for the internal limiting membrane, 4% of the 2-D scans had minor failures with no major failures using our approach, but 19% of the 2-D scans using the Stratus OCT-3 scanner had minor or complete failures.

Publication types

  • Evaluation Study

MeSH terms

  • Algorithms
  • Artificial Intelligence*
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Papilledema / pathology*
  • Pattern Recognition, Automated / methods*
  • Reproducibility of Results
  • Retina / pathology*
  • Sensitivity and Specificity
  • Surface Properties
  • Tomography, Optical Coherence / methods*