A case-controlled study of altered visual art production in Alzheimer's and FTLD

Cogn Behav Neurol. 2007 Mar;20(1):48-61. doi: 10.1097/WNN.0b013e31803141dd.

Abstract

Objective: To characterize dementia-induced changes in visual art production.

Background: Although case studies show altered visual artistic production in some patients with neurodegenerative disease, no case-controlled studies have quantified this phenomenon across groups of patients.

Method: Forty-nine subjects [18 Alzheimer disease, 9 frontotemporal dementia (FTD), 9 semantic dementia (SD), 15 healthy older controls (NC)] underwent formal neuropsychologic testing of visuospatial, perceptual, and creative functioning, and produced 4 drawings. Subjective elements of drawings were rated by an expert panel that was blind to diagnosis.

Results: Despite equal performance on standard visuospatial tests, dementia groups produced distinct patterns of artistic features that were significantly different from NCs. FTDs used more disordered composition and less active mark-making (P<0.05). Both FTDs and SDs drawings were rated as more bizarre and demonstrated more facial distortion than NCs (P<0.05). Also, SDs drastically failed a standardized test of divergent creativity. Alzheimer disease artwork was more similar to controls than to FTDs or SDs, but showed a more muted color palette (P<0.05) and trends toward including fewer details, less ordered compositions, and occasional facial distortion.

Conclusions: These group differences in artistic style likely resulted from disease-specific focal neurodegeneration, and elucidate the contributions of particular brain regions to the production of visual art.

Publication types

  • Comparative Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Alzheimer Disease / psychology*
  • Art*
  • Case-Control Studies
  • Creativity*
  • Dementia / classification
  • Dementia / psychology*
  • Female
  • Humans
  • Male
  • Matched-Pair Analysis
  • Middle Aged
  • Neuropsychological Tests
  • Reference Values
  • Visual Perception / physiology*