Abstract
High-speed, high-resolution optical coherence tomography (OCT) imaging of the human retina is demonstrated using a frequency-swept laser at 850 nm. A compact external cavity semiconductor laser design, optimized for swept-source ophthalmic OCT, is described. The laser enables an effective 16 kHz sweep rate with >10 mm coherence length and a tuning range of approximately 35 nm full width at half-maximum, yielding an axial resolution of <7 micro m in tissue.
Publication types
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Evaluation Study
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Research Support, N.I.H., Extramural
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Equipment Design
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Equipment Failure Analysis
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Humans
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Image Enhancement / instrumentation*
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Image Enhancement / methods
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Image Interpretation, Computer-Assisted / instrumentation*
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Image Interpretation, Computer-Assisted / methods
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Lasers*
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Reproducibility of Results
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Retina / cytology*
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Retinoscopes*
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Sensitivity and Specificity
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Tomography, Optical Coherence / instrumentation*
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Tomography, Optical Coherence / methods