Video documented follow-up of liver transplantation in Wilson's disease with predominant neurological manifestation

Mov Disord. 2007 May 15;22(7):1036-8. doi: 10.1002/mds.21444.

Abstract

Wilson's disease (WD) is a rare autosomal-recessive disorder of copper metabolism with predominantly hepatic and extrapyramidal motor symptoms. Copper chelating therapy has proven to be an effective treatment for WD. Yet, if conservative treatment fails, liver transplantation (LT) often is the only remaining therapeutic option. The indication for LT especially in patients with stable liver function but severe neurological manifestation is debated controversially. In this case report, we document the follow up of neurological symptoms in WD after LT for the first time on video.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Follow-Up Studies
  • Hepatolenticular Degeneration / pathology
  • Hepatolenticular Degeneration / physiopathology*
  • Hepatolenticular Degeneration / surgery*
  • Humans
  • Liver Transplantation / methods*
  • Male
  • Nervous System Diseases / physiopathology*
  • Nervous System Diseases / therapy*
  • Thalamus / pathology
  • Video Recording / methods